pentobarbital will lessen the extent or outcome of artemether/lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Coadministration with solid CYP3A4 inducers may lead to diminished serum concentrations and lack of antimalarial efficacy
Check Intently (1)pentobarbital will raise the degree or result of clopidogrel by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the level or outcome of levonorgestrel oral/ethinylestradiol/ferrous bisglycinate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. The efficacy of hormonal contraceptives can be lowered.
pentobarbital will lower the level or outcome of lumefantrine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with powerful CYP3A4 inducers can lead to decreased serum concentrations and loss of antimalarial efficacy
pentobarbital will minimize the extent or influence of copyright topical by influencing hepatic enzyme CYP2B6 metabolism. Minor/Importance Unidentified.
pentobarbital will decrease the level or outcome of quetiapine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
fentanyl transdermal and pentobarbital both enhance sedation. Avoid or Use Alternate Drug. Restrict use to patients for whom alternative remedy choices are inadequate
pentobarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral sort of equally brokers. Minimal/Importance Mysterious.
pentobarbital decreases levels of toremifene by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. CYP3A4 inducers maximize fee of toremifene metabolism, lowering the steady-condition focus in serum.
Contraindicated (1)pentobarbital will decrease the extent or impact of naloxegol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization website of naloxegol with strong CYP3A4 inducers is not really encouraged
Watch Carefully (one)pentobarbital will decrease the extent or impact of gefitinib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
With therapeutic doses of TCAs, barbiturates enhance metabolism and reduce blood concentrations of TCAs.
With therapeutic doses of TCAs, barbiturates raise metabolism and decrease blood concentrations of TCAs.
pentobarbital will decrease the extent or impact of zaleplon by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Importance Not known.